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I am convinced that senolytic agents will help change the face of regenerative medicine and for that matter most of medicine. More importantly they will dramatically increase success in Regenerative procedures. Let us again discuss senescent cells.

The American Academy of Stem Cell Physicians (AAOSCP) is honored to announce that Dr. Joseph Purita, a pioneer in the use of Stem Cell and PRP therapy for orthopedic conditions, has been awarded the prestigious “Stem Cell Scientist Physician Award.”

Until recently, bone marrow aspirate was essentially always concentrated.  However, there is now an ongoing debate between using bone marrow aspirate in a non-centrifuged manner and using it in a manner where it is concentrated by centrifugation. This question has generated much discussion and some

A few months ago, I wrote a blog on umbilical cord blood and placenta stem cell products being made available in the US. The central message was to exercise caution with these products, applying the principle of caveat emptor [buyer beware]

Calorie restriction remains the surest path to increased longevity and resilience to diseases of aging across many organisms including humans. As an added bonus, it is a good to lose those extra pounds especially during the holidays. Calorie restriction seems to affect many aging pathways.

The above diagram has an important take-home message, which is that physical therapy can accomplish many of the same tasks as stem cells.  What we have learned is that therapy, represented by “mechanical forces”, causes the formation of growth factors

What few people understand is that, as cells age, some of them degenerate into a population of poorly functioning senescent cells that accumulate throughout our body. There is no value to retaining these lingering senile cells.

We are constantly looking for ways to increase the stem cell output from bone marrow. We know all too well that most of the regenerative cells that we inject into the joint typically survive for only a short period of time.  Their release of growth factors is what gives

What can help increase longevity? We increase longevity by giving the cells more energy, increasing their telomere length, boosting the immune system, repairing DNA, and stimulating certain genes which foster longevity.

Short telomeres are associated with many different diseases ranging from cancer, osteoarthritis, diabetes, and many neurological conditions. Some of these neurological conditions may include Alzheimer’s Disease which is one of the scourges of